V. Adult T-cell Leukemia: Diagnosis and Treatment
نویسندگان
چکیده
منابع مشابه
Specific cutaneous manifestations in adult T cell leukemia/lymphoma
Background and aim: Adult T cell leukemia/lymphoma (ATLL) is an aggresive malignancy which may occur in human T lymphotropic virus1(HTLV1) infected persons. HTLV1 is endemic in Khorasan with prevalence of 2.3% in general population. Since specific cutaneous manifestations of lymphoma may occur in a significant number of patients, we studied ATLL patients in Mashhad.Mate...
متن کامل[Treatment of adult T-cell leukemia].
The treatment strategy for adult T-cell leukemia has not been established. CHOP derived combination chemotherapy protocols such as VEPA and VEPAM have failed to yield high complete remission rates and long survivals. Second or third generation combination chemotherapy regimens using alternative non-cross resistant drugs also have not achieved satisfactory results. A new multi-institutional tria...
متن کاملAltered expression of cell cycle regulators in adult T-cell leukemia/lymphoma patients
Abstract Background: Adult T-cell leukemia/lymphoma (ATLL) is caused by human T-cell lymphotropic virus type-1 (HTLV-1). HTLV-1 oncogenes can induce malignancy through controlled gene expression of cell cycle checkpoints in the host cell. HTLV-I genes play a pivotal role in overriding cell cycle checkpoints and deregulate cellular division. In this study, we aimed to determine and comp...
متن کاملAdult T-Cell Leukemia/Lymphoma (ATL): Pathogenesis, Treatment and Prognosis
Adult T-cell leukemia/lymphoma (ATL) was first described in 1977 as a distinct clinico‐ pathological entity with a suspected viral etiology. Subsequently, a RNA retrovirus, hu‐ man T-cell leukemia /lymphotropic virus type 1 (HTLV-1) was isolated as a carcinogenic pathogens [1]. HTLV-1 infects approximately 15 to 20 million people worldwide, with endemic areas in Japan, the Caribbean, and Africa...
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ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 2017
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.106.1397